Number of Declarable US Facilities

1. With listed agents:

< 60 Commercial Biologics Producers (for human/animal use, licensed or not)

< 50 Other Commercial Sites

<200 Research Sites (human agents); much overlap

<200 Research Sites (animal agents); much overlap (126 of these use Vesicular stomatitis virus (widely used as a model in research)).

<100 Research Sites (plant agents); much overlap (~45 of these use Xanthomonas campestris)

< 75 Biological Defense Program sites, government and contractors

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< 685 Total

Probable number of US sites with listed agents: ~ 550

(Could be reduced to about 379 by removing two cited agents from list)

2. With Microbial Production Capability >50 Liters:

~95 Commercial Biologics Producers

<90 Other Commercial Sites (pharmaceuticals/chemicals)

<107 Research and Government Sites

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< 292 Total

Probable number of US sites with microbial production capacity >50 liters: ~ 250 (About 30 of these also possess listed agents)

3. BW Defense Facilities and Contractors

200 (70 of these fall into the two categories above)

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Grand Total ~1000, less 100 overlap:

~ 900 Declarable US Facilities

(excluding aerosol facilities)