Annex A. Science And Technology Objectives (STOs)
Army Science and Technology Master Plan (ASTMP 1997)

III.J.01. Shigella Vaccines. By FY96, determine molecular features required for protective immunity against Shigella species. By FY97, select the best methodology for vaccine development. By FY97, transition to advanced development a candidate Shigella sonnei vaccine to protect 80 percent of immunized troops from dysentery caused by S. sonnei. By FY99, transition to advanced development a candidate S. flexneri vaccine to protect 80 percent of immunized troops from dysentery caused by S. flexneri in deployed forces worldwide.

Supports: Army Modernization Plan, Medical Annex O—Project, Sustain, and Protect the Force. The Medical Threat Facing a Force Projection Army (1994). Food and Drug Administration regulatory requirements.